Ivacaftor intermediate

Ivacaftor is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator gene, who account for 4–5% cases of cystic fibrosis.

13721-01-2:

52980-28-6:

873055-58-4:

Specifications:

Intermediate CAS No API/End Use Status Purity
Ethyl 4-Oxo-1,4-dihydroquinoline-3-carboxylate 52980-28-6 Ivacaftor Commercial 100%
4-oxo-1,4-dihydroquinoline-3-carboxylic acid 13721-01-2 Ivacaftor Commercial 98.26%
5-Amino-2,4-ditert-butylphenol 873055-58-4 Ivacaftor Lab Scale